Cannabigerolic Acid, or CBGA, is often called the “stem cell cannabinoid” because it serves as the starting point for many other major cannabinoids—including CBD, THC, and CBC—during the natural growth and maturation of the hemp plant. While CBGA typically converts into other cannabinoids with heat or time, interest in its raw, unheated form has grown as researchers explore its unique properties.
 

Early studies suggest that CBGA may interact with the body’s endocannabinoid system and other biological pathways in ways that could support balance and overall wellness. Scientists have examined CBGA in areas related to inflammation, metabolic function, and antioxidant activity, though much of this work remains preclinical and requires further study.
 

A 2022 Journal of Natural Products publication from Oregon State University gained attention when in-vitro findings showed CBGA (and CBDA) binding to the SARS-CoV-2 spike protein in laboratory conditions. These results are promising but preliminary, and additional research—especially in humans—is needed to better understand CBGA’s potential role.
 

Because it retains its natural acidic structure, CBGA is often included in raw or minimally heated hemp extracts. Many people explore CBGA for its potential to complement cannabinoid routines focused on balance, recovery, and general wellness.